New England Patriots vs. San Francisco 49ers: Odds and Computer Picks October 25, 2020

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The San Francisco 49ers (3-3) are just 2.5-point underdogs against the New England Patriots (2-3) on Sunday, October 25, 2020. The over/under is set at 45.5.

Game Info

Game Day: Sunday, October 25, 2020
Game Time: 4:25 PM ET
TV Channel: CBS
Location: Foxborough, MA
Stadium: Gillette Stadium

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Betting Information

Patriots vs 49ers Betting Information
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds	Favorite Moneyline	Underdog Moneyline
Patriots	-2.5	-115	-105	45.5	-110	-110	-143	123

Patriots Betting Insights

New England’s games have gone under the point total in three out of five opportunities this season (60%).
New England is just 2-3 against the spread.
The Patriots are 2-1 ATS when favored by at least 2.5 points.
The 49ers defense has allowed 21.7 points per game this season, about the same amount as the 21.8 the Patriots have scored.
In games where New England score at least 21.8 points this season, they are 1-1 overall and 1-1 against the spread.
When the San Francisco defense allows 21.7 points or fewer this year, the 49ers have pieced together a 3-0 overall record and a 3-0 record against the spread.

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49ers Betting Insights

Half of San Francisco’s games this year — three out of six — have gone over the point total.
San Francisco is 3-3 against the spread.
The 49ers are just 2-3 ATS when an underdog by at least 2.5 points.
The Patriots defense has allowed 22 points per game this season, close to the same amount as the 24.7 the 49ers have scored.
San Francisco is 2-0 overall and 2-0 against the spread when they score at least 24.7 points this season.
When New England allows opposing offenses to put 22 points or fewer on the scoreboard this year, they are 2-1 overall and 2-1 against the spread.

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Computer Picks

Computer picks for Patriots vs 49ers
ATS	Over/Under	Score Prediction
Patriots (-2.5)	Under (45.5)	Patriots 28 49ers 17

Total Facts

The Patriots’ average point total in outings this season is 43.8, 1.7 points below the over/under in this game.
The average point total for the 49ers this year is 0.8 points higher than this game’s over/under.
The Patriots and their opponents have combined to record more than this matchup’s over/under (45.5 points) in 40% of their games this season (two of five opportunities).
The 49ers have played in one games this year (out of six total matchups — 16.7% of opportunities) where they and their opponents combined to score at least 45.5 points.
The Patriots and the 49ers combine to average 1.0 more points per game than the total of 45.5 set for this game.
Opponents of the two teams average a combined 1.8 less points per game (43.7) than this game’s over/under of 45.5 points.

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Patriots vs 49ers: Last 5 Meetings

New England holds an edge against San Francisco over the past five matchups between these two squads, collecting a 4-1 record in those games. New England has had the scoring advantage in those five matchups, scoring 139 points while San Francisco put up 107.

Patriots vs 49ers: Last Five Meetings
Date	Home Team	Total Yards	Result
11/20/2016	49ers	444-299 NE	30-17 NE
12/16/2012	Patriots	520-388 NE	41-34 SF
10/5/2008	49ers	–	30-21 NE
1/2/2005	Patriots	–	21-7 NE
12/20/1998	Patriots	–	24-21 NE

Betting Insights: Last Three Games (Both Teams)

New England is just 1-2 against the spread and 1-2 straight up in their last three outcomes.
The under has been the norm for New England. They have failed to reach the total two times in their last three games.
The Patriots have averaged a total of 40.7 combined points over their last three games, 4.8 less than this game’s total of 45.5.
San Francisco has struggled to cover recently, going 1-2 against the spread and 1-2 straight up over their last three contests.
The under has been the norm for San Francisco. They have failed to reach the total two times in their last three games.
The 49ers have averaged a total of 48.3 combined points in their last three games, 2.8 greater than this game’s over/under of 45.5.

Injury Report

Patriots: FS Cody Davis: Out (Ribs), DT Beau Allen: Out (Undisclosed), G James Ferentz: Out (Illness), G Shaq Mason: Out (Illness), LB Brandon King: Out (Quadriceps), C David Andrews: Out (Thumb), DE Derek Rivers: Out (Illness), G Jermaine Eluemunor: Questionable (Ankle), WR Quincy Adeboyejo: Out (Undisclosed), DT Adam Butler: Questionable (Elbow), RB Sony Michel: Out (Illness), OT Yodny Cajuste: Out (Knee), DT Byron Cowart: Out (Illness), LB Josh Uche: Out (Foot), DL Michael Barnett: Out (Undisclosed)

49ers: OT Trent Williams: Questionable (Ankle), CB Richard Sherman: Out (Leg), TE Jordan Reed: Out (Knee), DE Ziggy Ansah: Out (Biceps), WR Tavon Austin: Out (Knee), C Ben Garland: Questionable (Calf), CB K’Waun Williams: Out (Knee), DE Dee Ford: Out (Back), C Weston Richburg: Out (Kneecap), CB Dontae Johnson: Questionable (Groin), SS Jaquiski Tartt: Questionable (Groin), RB Tevin Coleman: Out (Knee), OLB Kwon Alexander: Questionable (Ankle), OLB Mark Nzeocha: Out (Quadriceps), RB Raheem Mostert: Questionable (Ankle), DE Ronald Blair III: Out (Knee), DT Solomon Thomas: Out (Knee (acl)), WR Chris Thompson: Out (Undisclosed), DT Jullian Taylor: Out (Knee), RB Jeff Wilson Jr.: Questionable (Calf), DE Nick Bosa: Out (Acl), WR Jalen Hurd: Out (Knee), TE Chase Harrell: Out (Suspension)

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